RN COMPOUNDING CAL-D GLUCARATE 50G

RN COMPOUNDING CAL-D GLUCARATE 50G

For Extemporaneous Prescribing, 1ml scoop included

KEY FEATURES
– Calcium-D -glucarate is the calcium salt of D -glucaric acid, a substance produced
naturally in small amounts by mammals, including humans.
– Calcium-D -glucarate demonstrates detoxification properties, supporting the
excretion of potentially toxic compounds.
– Phase II detoxification facilitates excretion of chemical carcinogens, steroid hormones, and other lipid-soluble toxins via conjugation with glucuronic acid in the liver
(glucuronidation), allowing water soluble excretion into the intestinal lumen.
– Calcium-D -glucarate has been shown to inhibit beta-glucuronidase, an enzyme
produced by colonic microflora, capable of deconjugating bound toxins, making it
possible for them to be reabsorbed rather than excreted.
– Elevated beta-glucuronidase activity has been associated with an increased risk
for various cancers, particularly hormone dependent cancers such as breast, prostate,
and colon cancers (potentially due to accumulation of excess hormones and toxins).
– Calcium-D -glucarate’s inhibition of betaglucuronidase activity allows the body to
successfully excrete excess hormones (such as oestrogens) before they can be reabsorbed, reactivated and recirculated within the body

DOSEAGE
– 300MG – 3G/DAY

STATEMENTS AND WARNINGS
Many drugs and hormones are metabolised in the liver via glucuronidation therefore, taking
calcium-D -glucarate may increase elimination of these substances, possibly reducing their effectiveness.Cal-D – Glucarate has not been extensively tested for its effects during pregnancy. Health practitioners may prefer to avoid its use during pregnancy or lactation, unless confident that its impact can be reasonably deemed to be safe or beneficial.